Objective: To review cases of retinoblastoma.
Setting: Department of Pathology Aga Khan University Hospital Karachi.
Method: Twenty-three specimens from cases of retinoblastoma received over a period of eight years were routinely processes and stained with haematoxylin and Eosin stain. Other stains were used for tuberculoses and melanin. Immunochemistry was resorted to in undifferentiated tumors.
Results: Over 60% cases of retinoblastoma were diagnosed after 5 years and nine cases showed involvement of optinerve.
Conclusion: Late diagnosis of retinoblastoma effects the stage of the tumors and the prognosis.