A case of haemophagocytic syndrome and Kikuchi-Fujimoto disease occurring concurrently in a 17-year-old female

Int J Clin Pract. 2000 Oct;54(8):547-9.

Abstract

An unusual case in which a young Asian female presenting with fever, lymphadenopathy and cytopaenia was found to have distinct histological features of both haemophagocytic syndrome (HS) and histiocytic necrotising lymphadenitis (Kikuchi-Fujimoto disease, KFD) is presented. We review the clinical features of each of these rare, but important, diagnoses and propose the hypothesis that they may form part of a disease continuum, rather than representing separate entities.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Biopsy
  • Bone Marrow Cells / pathology
  • Disease Progression
  • Female
  • Histiocytic Necrotizing Lymphadenitis / complications*
  • Histiocytic Necrotizing Lymphadenitis / diagnosis
  • Histiocytosis, Non-Langerhans-Cell / complications*
  • Histiocytosis, Non-Langerhans-Cell / diagnosis
  • Humans
  • Lymph Nodes / pathology