A novel method of cross-linking ultra-high-molecular-weight polyethylene to improve wear, reduce oxidation, and retain mechanical properties. Recipient of the 1999 HAP Paul Award

J Arthroplasty. 2001 Feb;16(2):149-60. doi: 10.1054/arth.2001.20540.

Abstract

Increasing cross-linking has been shown in vitro and in vivo to improve markedly the wear resistance of ultra-high-molecular-weight polyethylene (UHMWPE). The reduction in the mechanical properties of polyethylene under certain methods used to produce cross-linking has been a concern, however. These reductions are known to result from the processes used to increase the cross-link density and could affect the device performance in vivo. We present a novel method of increasing the cross-link density of UHMWPE in which UHMWPE is irradiated in air at an elevated temperature with a high-dose-rate electron beam and subsequently is melt-annealed. This treatment improves markedly the wear resistance of the polymer as tested in a hip simulator, while maintaining the mechanical properties of the material within national and international standards. This method leads to the absence of detectable free radicals in the polymer and, as a result, excellent resistance to oxidation of the polymer.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biocompatible Materials / chemistry*
  • Biocompatible Materials / radiation effects
  • Computer Simulation
  • Free Radicals / chemistry
  • Hip Prosthesis* / standards
  • Humans
  • Materials Testing
  • Microscopy, Electron, Scanning
  • Oxidation-Reduction
  • Polyethylenes / chemistry*
  • Polyethylenes / radiation effects
  • Prosthesis Design
  • Surface Properties

Substances

  • Biocompatible Materials
  • Free Radicals
  • Polyethylenes