Nonhomologous end-joining proteins are required for V(D)J recombination, normal growth, and neurogenesis

Cold Spring Harb Symp Quant Biol. 1999:64:169-81. doi: 10.1101/sqb.1999.64.169.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Antigens, Nuclear*
  • Apoptosis
  • DNA Helicases*
  • DNA Repair
  • DNA-Binding Proteins / deficiency
  • DNA-Binding Proteins / genetics
  • DNA-Binding Proteins / metabolism
  • Gene Rearrangement, B-Lymphocyte*
  • Gene Rearrangement, T-Lymphocyte*
  • Growth
  • Homeodomain Proteins / genetics
  • Homeodomain Proteins / metabolism
  • Ku Autoantigen
  • Mice
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Mutation
  • Nervous System / cytology
  • Nervous System / embryology
  • Nuclear Proteins / deficiency
  • Nuclear Proteins / genetics
  • Phenotype
  • Proteins / metabolism
  • Recombination, Genetic*
  • Tumor Suppressor Protein p53 / deficiency
  • Tumor Suppressor Protein p53 / genetics

Substances

  • Antigens, Nuclear
  • DNA-Binding Proteins
  • Homeodomain Proteins
  • Nuclear Proteins
  • Proteins
  • Rag2 protein, mouse
  • Tumor Suppressor Protein p53
  • V(D)J recombination activating protein 2
  • XRCC4 protein, human
  • RAG-1 protein
  • DNA Helicases
  • XRCC5 protein, human
  • Xrcc6 protein, human
  • Xrcc6 protein, mouse
  • Ku Autoantigen