Abstract
A simple and sensitive method for the polarographic determination of praziquantel (1) after derivatization using Vilsmeier formylation is described. The polarographically active compound obtained by this procedure has been separated, identified and prepared using N,N-dimethylformamide and phosphorus oxychloride.
MeSH terms
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Antiplatyhelmintic Agents / analysis*
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Antiplatyhelmintic Agents / chemistry
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Dimethylformamide
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Electrodes
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Formates / analysis
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Formates / chemical synthesis
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Phosphorus Compounds
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Polarography
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Praziquantel / analysis*
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Praziquantel / chemistry
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Spectrophotometry, Ultraviolet
Substances
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Antiplatyhelmintic Agents
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Formates
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Phosphorus Compounds
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Praziquantel
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Dimethylformamide
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phosphoryl chloride