Abstract
Many atypical forms of sarcoidosis have been described. mediastinum-lung involvement, observed in 90% of the cases, may cause atypical manifestations: hemoptysis, chest pain, predominant pleural or proximal bronchial involvement. Diffuse "unpolished glass" images or air cavities may be observed on the chest x-ray. A rigorous diagnostic work-up is necessary for these atypical forms. Pathological confirmation is mandatory: non-caseous tuberculoid granuloma. A very wide range of extra-thoracic localizations have been described with variable clinical manifestations. In cases with no mediastinum-lung involvement, pathology data must be confronted with the notion of multiple organ dissemination to reach diagnosis.
MeSH terms
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Biopsy
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Bronchoalveolar Lavage Fluid / cytology
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Chest Pain / etiology
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Endocrine System Diseases / classification*
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Endocrine System Diseases / complications
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Endocrine System Diseases / diagnosis*
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Gastrointestinal Diseases / classification*
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Gastrointestinal Diseases / complications
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Gastrointestinal Diseases / diagnosis*
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Hematologic Diseases / classification*
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Hematologic Diseases / complications
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Hematologic Diseases / diagnosis*
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Hemoptysis / etiology
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Humans
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Joint Diseases / classification*
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Joint Diseases / complications
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Joint Diseases / diagnosis*
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Lung Diseases / classification*
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Lung Diseases / complications
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Lung Diseases / diagnosis*
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Mediastinal Diseases / classification*
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Mediastinal Diseases / complications
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Mediastinal Diseases / diagnosis*
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Sarcoidosis / classification*
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Sarcoidosis / complications
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Sarcoidosis / diagnosis*
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Tomography, X-Ray Computed