Induction of T-cell apoptosis by polyurethane biomaterials used in left ventricular assist devices is dependent on calcineurin activation

Transplant Proc. 2001 Feb-Mar;33(1-2):1958-9. doi: 10.1016/s0041-1345(00)02753-6.
No abstract available

MeSH terms

  • Apoptosis / physiology*
  • Biocompatible Materials*
  • Calcineurin / metabolism*
  • Cell Nucleus / metabolism
  • Cyclosporine / pharmacology
  • DNA-Binding Proteins / metabolism
  • Heart-Assist Devices*
  • Humans
  • Immunosuppressive Agents / pharmacology
  • Lymphocyte Activation / drug effects
  • NFATC Transcription Factors
  • Nuclear Proteins*
  • Polyurethanes / pharmacology*
  • T-Lymphocytes / drug effects*
  • T-Lymphocytes / physiology
  • Transcription Factors / metabolism

Substances

  • Biocompatible Materials
  • DNA-Binding Proteins
  • Immunosuppressive Agents
  • NFATC Transcription Factors
  • Nuclear Proteins
  • Polyurethanes
  • Transcription Factors
  • Cyclosporine
  • Calcineurin