Abstract
We have isolated a new chicken gene that is a member of the cysteine-rich secreted protein family (CRISP). The CRISP family is composed of over 70 members that are found in many phyla of organisms, including: vertebrates, plants, fungi, yeast, and insects. Here we describe the cloning of a novel member of this family, SugarCrisp, and its expression pattern throughout chicken embryogenesis. We also describe its utility as a marker of thyroid and pancreatic mesoderm in the developing chicken embryo and its expression within the human and mouse in glandular tissue.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Amino Acid Sequence
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Animals
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Avian Proteins*
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Chick Embryo
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Cloning, Molecular
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Cysteine / chemistry*
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DNA, Complementary / metabolism
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Embryo, Nonmammalian / metabolism
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Humans
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In Situ Hybridization
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Lung / embryology
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Mesoderm / metabolism*
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Molecular Sequence Data
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Pancreas / embryology*
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Protein Biosynthesis*
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Proteins / chemistry*
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Proteins / metabolism
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Sequence Homology, Amino Acid
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Thyroid Gland / embryology*
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Tissue Distribution
Substances
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Avian Proteins
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DNA, Complementary
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Proteins
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SugarCrisp protein, chicken
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Cysteine
Associated data
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GENBANK/AF329195
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GENBANK/AF329196