Protein import into plant mitochondria: precursor proteins differ in ATP and membrane potential requirements

Plant Mol Biol. 2001 Feb;45(3):317-25. doi: 10.1023/a:1006456115140.

Abstract

The import pathways of the alternative oxidase and the F(A)d subunit of the ATP synthase from soybean were characterised. The F(A)d precursor does not require extramitochondrial ATP for import and this was shown to be a characteristic of the mature protein. The alternative oxidase and F(A)d precursors were shown to differ in their requirement for a membrane potential. The membrane potential was modified using malonate, a competitive inhibitor to complex II. The alternative oxidase could be imported at higher malonate concentrations compared to the F(A)d. This difference could not be ascribed to the number of positive charges in each presequence as would be predicted from similar studies in fungi.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenosine Triphosphate / metabolism
  • Biological Transport
  • Enzyme Precursors / metabolism
  • Glycine max
  • Intracellular Membranes / physiology
  • Membrane Potentials
  • Mitochondria / metabolism*
  • Mitochondrial Proteins
  • Oxidoreductases / metabolism
  • Plant Proteins / metabolism*
  • Protein Processing, Post-Translational
  • Protein Subunits
  • Proton-Translocating ATPases / metabolism

Substances

  • Enzyme Precursors
  • Mitochondrial Proteins
  • Plant Proteins
  • Protein Subunits
  • Adenosine Triphosphate
  • Oxidoreductases
  • alternative oxidase
  • Proton-Translocating ATPases