The authors present their initial experience with a compact open magnetic resonance (MR) image-guided system, (PoleStar N-10, Odin Medical Technologies, Yokneam, Israel) used in a standard operating room, modified for radio frequency (RF) shielding. The low intensity of the magnetic field (0.12T), and the ability to lower the magnet from the operative field during surgery allows for an almost routine surgical procedure, in addition to the benefits of using intraoperative MR imaging. Although an MR compatible anesthesia machine and monitoring system are used, the system offers anesthesiologists access to the patient at all times during the procedure, and the ability to use conventional surgical equipment, syringe pumps, and warming devices. Propofol and remifentanil, used for maintaining anesthesia, allow early extubation and neurological evaluation at the end of surgery. Electrocorticographic monitoring can be used during surgery for epilepsy, and awake craniotomy can be performed. More experience with this new imaging system is required to assess its influence on clinical decision making and outcome.