Authors evaluate the indications and results of percutaneous puncture and drainage of pancreatic pseudocysts. The interventions were performed in 20 patients. The first line treatment is usually surgical. Percutaneous drainage or aspiration is suggested if the patient is symptomatic, the size of pseudocyst is between 3 and 6 cms and when it can be punctured using radiological procedures, without the risk of damaging other organs. Previous peripancreatic operation, high-risk surgical intervention and the refusal of the operation by the patient should also be considered. Percutaneous drainage is an alternative method for the treatment of pancreatic pseudocysts. The advantages of this procedure are: It is minimally invasive, complications are rare and reintervention is possible. Disadvantage is high risk of recurrence.