Metastatic phaeochromocytoma: risks of diagnostic needle puncture and treatment by arterial embolisation

J Hum Hypertens. 2001 Mar;15(3):209-11. doi: 10.1038/sj.jhh.1001151.

Abstract

A 62-year-old man had an acute episode of hypertension 72 h after fine needle aspiration biopsy of an intra- hepatic nodule. The patient had been operated 3 years previously for a right adrenal phaeochromocytoma with no evidence of metastases at that time. Thus, a relapse of the tumour was postulated and confirmed by raised levels of urinary metanephrines. The extent of the metastases precluded surgical intervention and thus localised embolisation was proposed and permitted a clinical stabilisation over 8 months. This case indicates the necessity of long-term post-operative follow-up of phaeochromocytoma as well as the dangers of fine needle aspiration biopsy of metastases from this kind of tumour. Treatment of malignant phaeochromocytoma is difficult and embolisation was a useful therapeutic alternative in this case where the metastases were well defined.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Gland Neoplasms / pathology*
  • Adrenal Gland Neoplasms / therapy
  • Adrenal Glands / pathology*
  • Biopsy, Needle / adverse effects
  • Embolization, Therapeutic
  • Humans
  • Hypertension / pathology
  • Hypertension / physiopathology*
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / pathology
  • Neoplasm Recurrence, Local / therapy
  • Pheochromocytoma / pathology*
  • Pheochromocytoma / therapy