In-vivo quantitative hydrolipidic map of perirenal adipose tissue by chemical shift imaging at 4.7 Tesla

Int J Obes Relat Metab Disord. 2001 Apr;25(4):457-61. doi: 10.1038/sj.ijo.0801262.

Abstract

Objective: In this work, chemical shift magnetic resonance imaging is used for in vivo quantitative evaluation of fat and water content in the perirenal white adipose tissue.

Design and measurements: Experiments were carried out on female Sprague-Dawley rats with a 4.7 T magnet. Fat and water fractions were computed pixel-by-pixel from the chemical shift selective images with an algorithm of reconstruction that allowed parametric maps (called hydrolipidic maps) to be produced with a pixel size of 625 x 625 microm.

Results: Our findings indicate that, in the perirenal adipose tissue, the water content ranges between 15% and 20%, with slight differences between the ventral and dorsal portions, and between the left and right deposits. The mesenteric adipose tissue, observed for comparison, has a mean water content of 30%.

Conclusion: The present work demonstrates that methods based on magnetic resonance imaging can be useful tools for non-invasive in vivo quantitative mapping of the hydrolipidic content of adipose tissues.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adipose Tissue / anatomy & histology*
  • Adipose Tissue / chemistry
  • Algorithms
  • Animals
  • Body Water / chemistry*
  • Female
  • Kidney
  • Lipids / analysis*
  • Magnetic Resonance Imaging
  • Phantoms, Imaging
  • Rats
  • Rats, Sprague-Dawley

Substances

  • Lipids