Remission of metastatic cervical adenocarcinoma with weekly paclitaxel

Int J Gynecol Cancer. 2001 Mar-Apr;11(2):167-8. doi: 10.1046/j.1525-1438.2001.011002167.x.

Abstract

We report the use of paclitaxel in the successful treatment of a patient with recurrent adenocarcinoma of the cervix. Paclitaxel, 70 mg/m2 by 1-h infusion weekly, was administered to a 59-year-old patient with cervical adenocarcinoma showing lung metastasis. She showed partial clinical response after seven cycles, and at the completion of 20 cycles she showed complete response, which was confirmed by chest X-ray and computed tomography scan. Toxicities including neurotoxicity were mild. She showed an objective response to treatment for over 8 months, and she enjoyed a favorable quality of life during and after treatment. Weekly paclitaxel was very well tolerated, yet was effective for recurrent cervical adenocarcinoma.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / drug therapy*
  • Adenocarcinoma / pathology
  • Adenocarcinoma / secondary*
  • Antineoplastic Agents, Phytogenic / administration & dosage
  • Antineoplastic Agents, Phytogenic / therapeutic use*
  • Drug Administration Schedule
  • Female
  • Humans
  • Lung Neoplasms / secondary*
  • Middle Aged
  • Neoplasm Recurrence, Local / drug therapy
  • Paclitaxel / administration & dosage
  • Paclitaxel / therapeutic use*
  • Uterine Cervical Neoplasms / drug therapy*
  • Uterine Cervical Neoplasms / pathology

Substances

  • Antineoplastic Agents, Phytogenic
  • Paclitaxel