Acute pancreatitis associated with interferon alpha therapy for chronic myelogenous leukemia

Leuk Lymphoma. 2000 Nov;39(5-6):647-50. doi: 10.3109/10428190009113396.

Abstract

Acute pancreatitis related to interferon alpha therapy is very rare. We report two patients with chronic myelogenous leukemia (CML) who developed acute pancreatitis following treatment with interferon alpha. A review of the literature on the association of pancreatitis and interferon alpha is provided. Possible pathophysiologic mechanisms are also discussed.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adult
  • Humans
  • Interferon-alpha / adverse effects*
  • Interferon-alpha / therapeutic use
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / complications*
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / drug therapy
  • Male
  • Pancreatitis / chemically induced*
  • Pancreatitis / diagnostic imaging
  • Pancreatitis / pathology
  • Tomography, X-Ray Computed

Substances

  • Interferon-alpha