Anti-interferon gamma action of epigallocatechin-3-gallate mediated by specific inhibition of STAT1 activation

FASEB J. 2001 May;15(7):1309-11. doi: 10.1096/fj.00-0519fje.

Authors

M Menegazzi¹, E Tedeschi, D Dussin, A C De Prati, E Cavalieri, S Mariotto, H Suzuki

Affiliation

¹ Biochemistry Section, Department of Neuroscience and Vision, University of Verona, I-37134 Verona, Italy.

PMID: 11344123
DOI: 10.1096/fj.00-0519fje

No abstract available

MeSH terms

Antineoplastic Agents / pharmacology*
Catechin / analogs & derivatives
Catechin / pharmacology*
DNA-Binding Proteins / antagonists & inhibitors
DNA-Binding Proteins / metabolism*
Enzyme Inhibitors / pharmacology*
Humans
Immunoblotting
Interferon-gamma / antagonists & inhibitors
Interferon-gamma / metabolism*
Nitric Oxide Synthase / metabolism
Nitric Oxide Synthase Type II
Phosphorylation
STAT1 Transcription Factor
Signal Transduction / drug effects
Signal Transduction / physiology*
Trans-Activators / antagonists & inhibitors
Trans-Activators / metabolism*
Tumor Cells, Cultured

Substances

Antineoplastic Agents
DNA-Binding Proteins
Enzyme Inhibitors
STAT1 Transcription Factor
STAT1 protein, human
Trans-Activators
Interferon-gamma
Catechin
epigallocatechin gallate
NOS2 protein, human
Nitric Oxide Synthase
Nitric Oxide Synthase Type II