The present status of liver transplantation in th UK is described based on our clinical experience in the Liver Unit, Queen Elizabeth Hospital. In 1999, there were 161 cadaveric liver transplantations in the Liver Unit. The shortage of suitable donors for transplantation is widely recognized and is a worldwide problem. In order to solve this problem, "marginal donors" who would usually be refused on medical grounds have been used, and split-liver transplantation procedures have been developed in the Liver Unit.