Effects of synthetic cecropin analogs on in vitro growth of Acholeplasma laidlawii

Antimicrob Agents Chemother. 2001 Jun;45(6):1894-5. doi: 10.1128/AAC.45.6.1894-1895.2001.

Abstract

Four synthetic peptides (Peptidyl MIMs; Demeter Biotechnologies, Inc.) were evaluated for their in vitro activity against Acholeplasma laidlawii. Fifty percent effective concentration values ranged from 1 to 15 microM. Three of these compounds are more lethal than cecropin B against A. laidlawii.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Acholeplasma laidlawii / drug effects*
  • Acholeplasma laidlawii / growth & development*
  • Anti-Bacterial Agents / pharmacology*
  • Insect Proteins / pharmacology*

Substances

  • Anti-Bacterial Agents
  • Insect Proteins
  • cecropin B protein, Insecta