Objective: To study the treatment of women with gestational impared glucose tolerance (GIGT) in relation to outcome of fetus and newborns.
Methods: 98 women with GIGT were randomized into untreated (37 mothers) and treated groups (61 mothers) that included diet control and insulin therapy. The perinatal outcomes were compared in the two groups.
Results: The incidence of macrosomia (P < 0.01) and fetal distress (P < 0.05) was found to be significantly higher in the untreated group when compared with the treated group. The prevalence of neonatal metabolic complications in the untreated group was higher than that of the treated group as well.
Conclusion: Treatment of women with GIGT will reduce adverse outcome in pregnancy.