Sleep disturbances and mortality: results from the Canadian Study of Health and Aging

J Am Geriatr Soc. 2001 May;49(5):639-41. doi: 10.1046/j.1532-5415.2001.49125.x.

Abstract

Objectives: To cross-validate, in a secondary analysis, the observation that daytime sleepiness is associated with an increased risk of death.

Design: Prospective cohort study.

Setting: Canada, a nationally representative sample of people age 65 and older.

Participants: Nine thousand and eight community-dwelling participants in the Canadian Study of Health and Aging.

Exposures: self-reported sleep disturbances.

Outcomes: Cox hazard ratios (HRs) for death.

Results: The unadjusted analysis showed a small increased risk of death from daytime sleepiness (HR = 1.89; 95% confidence interval (CI) = 1.44-2.46), but this finding did not persist in a multivariate model adjusted for age, depression, cognition, comorbid illness, and function.

Conclusion: Daytime sleepiness itself is not associated with an increased risk of death when other factors are taken into account. Daytime sleepiness may be a proxy for other morbid conditions and therefore for overall tiredness.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Activities of Daily Living
  • Age Distribution
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Aging
  • Canada / epidemiology
  • Cognition Disorders / complications
  • Comorbidity
  • Depression / complications
  • Fatigue / complications*
  • Fatigue / epidemiology*
  • Female
  • Geriatric Assessment
  • Humans
  • Male
  • Mass Screening
  • Mortality*
  • Multivariate Analysis
  • Population Surveillance
  • Prevalence
  • Proportional Hazards Models
  • Prospective Studies
  • Risk Factors
  • Sleep Wake Disorders / complications*
  • Sleep Wake Disorders / epidemiology*
  • Surveys and Questionnaires
  • Survival Analysis