Abstract
A review of the records of 23 patients with squamous cell carcinoma of the oral tongue and floor of mouth treated with irradiation after excisional biopsy has shown that: (a) Radiotherapy, primarily using interstitial radium implants, results in excellent local control of the primary area (100%) with preservation of function. (b) The frequency and severity of soft-tissue and bone necrosis may be reduced by not exceeding 5,500-6,000 rads from radium implants when only subclinical aggregates of cancer cells are probably present. (c) Theincidence of subsequent neck disease is low-8.7% (2 of 23 patients), and does not warrant routine elective irradiation of the cervical lymphatics.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adult
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Aged
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Biopsy
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Carcinoma, Squamous Cell / mortality
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Carcinoma, Squamous Cell / radiotherapy*
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Carcinoma, Squamous Cell / surgery
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Female
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Gold Radioisotopes / therapeutic use
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Humans
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Lung Neoplasms / mortality
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Male
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Mandibular Diseases / etiology
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Middle Aged
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Mouth Floor*
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Mouth Neoplasms / mortality
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Mouth Neoplasms / radiotherapy*
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Mouth Neoplasms / surgery
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Necrosis / etiology
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Neoplasm Metastasis
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Osteoradionecrosis / etiology
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Radiotherapy / adverse effects
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Radiotherapy Dosage
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Radium / therapeutic use
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Tongue Neoplasms / mortality
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Tongue Neoplasms / radiotherapy*
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Tongue Neoplasms / surgery
Substances
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Gold Radioisotopes
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Radium