Local vs systemic corticosteroids in the treatment of carpal tunnel syndrome

S M Wong; A C Hui; A Tang; P C Ho; L K Hung; K S Wong; R Kay; E Li

doi:10.1212/wnl.56.11.1565

Local vs systemic corticosteroids in the treatment of carpal tunnel syndrome

Neurology. 2001 Jun 12;56(11):1565-7. doi: 10.1212/wnl.56.11.1565.

Authors

S M Wong¹, A C Hui, A Tang, P C Ho, L K Hung, K S Wong, R Kay, E Li

Affiliation

¹ Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, China. [email protected]

PMID: 11402116
DOI: 10.1212/wnl.56.11.1565

Abstract

The authors compared the effectiveness of low-dose, short-term oral prednisolone vs local methylprednisolone injection in a prospective, double-blinded, parallel treatment study of carpal tunnel syndrome (CTS). A single injection of 15 mg methylprednisolone resulted in significant improvement in global symptom scores over a 12-week period. This study demonstrated the superiority of local steroid injection to oral steroid in the treatment of CTS.

Publication types

Clinical Trial
Comparative Study
Randomized Controlled Trial

MeSH terms

Administration, Oral
Anti-Inflammatory Agents / administration & dosage*
Carpal Tunnel Syndrome / drug therapy*
Double-Blind Method
Female
Humans
Injections, Intra-Articular
Male
Methylprednisolone / administration & dosage*
Middle Aged
Prednisolone / administration & dosage*
Prospective Studies

Substances

Anti-Inflammatory Agents
Prednisolone
Methylprednisolone