MR imaging of intrahepatic cholangiocarcinoma: use of ferumoxides for lesion localization and extension

H J Braga; K Imam; D A Bluemke

doi:10.2214/ajr.177.1.1770111

MR imaging of intrahepatic cholangiocarcinoma: use of ferumoxides for lesion localization and extension

AJR Am J Roentgenol. 2001 Jul;177(1):111-4. doi: 10.2214/ajr.177.1.1770111.

Authors

H J Braga¹, K Imam, D A Bluemke

Affiliation

¹ Department of Radiology, Johns Hopkins University School of Medicine, Johns Hopkins Hospital, 600 N. Wolfe St., Baltimore, MD 21287, USA.

PMID: 11418408
DOI: 10.2214/ajr.177.1.1770111

Abstract

Objective: The purpose of this study was to evaluate the use of ferumoxides in the visualization and localization of intrahepatic cholangiocarcinoma.

Conclusion: The contrast-to-noise ratio of cholangiocarcinoma compared with that of the adjacent liver significantly (p < 0.03) improves after ferumoxides administration. Ferumoxides-enhanced MR imaging is a useful technique for the visualization and localization of intrahepatic cholangiocarcinoma.

Publication types

Clinical Trial

MeSH terms

Aged
Bile Duct Neoplasms / pathology*
Bile Ducts, Intrahepatic*
Cholangiocarcinoma / pathology*
Contrast Media*
Dextrans
Female
Ferrosoferric Oxide
Humans
Iron*
Magnetic Resonance Imaging*
Magnetite Nanoparticles
Male
Middle Aged
Oxides*

Substances

Contrast Media
Dextrans
Magnetite Nanoparticles
Oxides
Iron
ferumoxides
Ferrosoferric Oxide