ABC transporters and the export of capsular polysaccharides from gram-negative bacteria

Res Microbiol. 2001 Apr-May;152(3-4):357-64. doi: 10.1016/s0923-2508(01)01207-4.

Abstract

In this review, we discuss the kps cluster of Escherichia coli as the paradigm for the ABC capsular polysaccharide exporter (CPSE) family. Components of the cluster form a multimeric protein complex consisting of both biosynthetic and export machinery. We compare the Kps exporter with capsule export systems from other members of the CPSE family.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • ATP-Binding Cassette Transporters / genetics
  • ATP-Binding Cassette Transporters / metabolism*
  • Bacterial Outer Membrane Proteins / metabolism
  • Bacterial Proteins / metabolism
  • Escherichia coli / genetics
  • Escherichia coli / metabolism*
  • Escherichia coli / pathogenicity
  • Escherichia coli Proteins / metabolism*
  • Gram-Negative Bacteria / genetics
  • Gram-Negative Bacteria / metabolism*
  • Membrane Transport Proteins
  • Periplasmic Proteins*
  • Polysaccharides, Bacterial / genetics
  • Polysaccharides, Bacterial / metabolism*

Substances

  • ATP-Binding Cassette Transporters
  • Bacterial Outer Membrane Proteins
  • Bacterial Proteins
  • Escherichia coli Proteins
  • KpsD protein, E coli
  • Membrane Transport Proteins
  • Periplasmic Proteins
  • Polysaccharides, Bacterial
  • tolC protein, E coli