Understanding the interaction between environmental exposures and molecular events in colorectal carcinogenesis

Cancer Invest. 2001;19(5):524-39. doi: 10.1081/cnv-100103850.
No abstract available

Publication types

  • Review

MeSH terms

  • Adenoma / chemically induced
  • Adenoma / genetics
  • Anti-Inflammatory Agents, Non-Steroidal / pharmacology
  • Apoptosis / drug effects
  • Carcinoma / chemically induced
  • Carcinoma / genetics
  • Cell Cycle Proteins*
  • Cell Transformation, Neoplastic / chemically induced
  • Cell Transformation, Neoplastic / genetics
  • Colorectal Neoplasms / chemically induced*
  • Colorectal Neoplasms / genetics*
  • Cyclin-Dependent Kinase Inhibitor p27
  • Dietary Fiber / administration & dosage
  • Environmental Exposure / adverse effects*
  • Enzyme Inhibitors / pharmacology
  • Folic Acid / metabolism
  • Genes, APC / drug effects
  • Genes, DCC / genetics
  • Genes, Tumor Suppressor / drug effects*
  • Genes, bcl-2 / drug effects
  • Genes, p53 / genetics
  • Genes, ras / genetics
  • Humans
  • Methylation
  • Methylenetetrahydrofolate Reductase (NADPH2)
  • Microtubule-Associated Proteins / genetics
  • Mutation* / drug effects
  • Oxidoreductases Acting on CH-NH Group Donors / genetics
  • Smoking / adverse effects
  • Tumor Suppressor Proteins*

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Cell Cycle Proteins
  • Dietary Fiber
  • Enzyme Inhibitors
  • Microtubule-Associated Proteins
  • Tumor Suppressor Proteins
  • Cyclin-Dependent Kinase Inhibitor p27
  • Folic Acid
  • Oxidoreductases Acting on CH-NH Group Donors
  • Methylenetetrahydrofolate Reductase (NADPH2)