Abstract
This study describes the clinical characteristics of tularemia in Spain's first epidemic outbreak and the therapeutic response and compares the efficacy of 3 antibiotics (streptomycin, ciprofloxacin, and doxycycline). For 142 cases of tularemia, the therapeutic failure rate was 22.5%; ciprofloxacin was the antibiotic with the lowest percentage of therapeutic failures and with the fewest side effects.
MeSH terms
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Adolescent
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Adult
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Aged
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Anti-Bacterial Agents / therapeutic use*
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Antibodies, Bacterial / blood
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Disease Outbreaks*
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Female
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Francisella tularensis / immunology
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Francisella tularensis / isolation & purification*
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Humans
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Male
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Middle Aged
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Spain / epidemiology
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Treatment Outcome
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Tularemia / drug therapy
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Tularemia / epidemiology*
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Tularemia / microbiology
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Tularemia / physiopathology
Substances
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Anti-Bacterial Agents
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Antibodies, Bacterial