Objective: This research aimed at observing the persistent time of ADRV antibody in the sera of ADRV cases.
Methods: We adopted a sensitive and specific Enzyme-linked immunosorbent assay (ELISA) for detecting ADRV antibody in patients who had recovered.
Results: We tested 260 human sera from Yi-Ma town of Henan Province. One year, six years and ten years after the patients had recovered, the of positive rates for ADRV antibody were respectively 27.7%, 36.3% and 23.3%. Thirty subjects of ADRV antibody positive were followed up retrospectively, no recurrent diarrhea was found.
Conclusions: The ADRV antibody can last 16 years after primary infection.