Treatment efficacy of intermittent claudication by surgical intervention, supervised physical exercise training compared to no treatment in unselected randomised patients I: one year results of functional and physiological improvements

Eur J Vasc Endovasc Surg. 2001 Aug;22(2):107-13. doi: 10.1053/ejvs.2001.1413.

Abstract

Objectives: to compare the effect of surgery, exercise and simple observation on maximum exercise power in claudicants.

Design: prospective, randomised study.

Methods: a total of 264 unselected claudicants were randomised to supervised exercise training, invasive treatment (open surgical or endovascular procedures) or observation. One year treatment outcomes were analysed on an intention to-treat basis.

Results: invasively treated patients showed a significant improvement in maximum walking power, stopping distance, post-ischaemic blood flow and big toe pressure at one year. Patients randomised to physical exercise training or to the control group did not improve in any outcome measure.

Conclusion: invasive treatment increased walking capacity, leg blood pressure and flow. Supervised physical exercise training offered no therapeutic advantage compared to untreated controls.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Exercise Test
  • Exercise*
  • Female
  • Follow-Up Studies
  • Humans
  • Intermittent Claudication / surgery*
  • Male
  • Middle Aged
  • Prospective Studies
  • Quality of Life
  • Treatment Outcome