Pedophilia is accompanied by increased plasma concentrations of catecholamines, in particular epinephrine

Psychiatry Res. 2001 Aug 5;103(1):43-9. doi: 10.1016/s0165-1781(01)00268-2.

Abstract

Plasma epinephrine and norepinephrine concentrations were measured in pedophiles and normal men both in placebo conditions and after administration of meta-chlorophenylpiperazine (mCPP), a post-synaptic 5-HT2 receptor agonist. The plasma concentrations of catecholamines, in particular epinephrine, were significantly increased in pedophiles. It is concluded that pedophiles may have an increased activity of the sympathoadrenal system.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Catecholamines / blood*
  • Catecholamines / metabolism
  • Epinephrine / blood*
  • Epinephrine / metabolism
  • Humans
  • Male
  • Pedophilia / blood*
  • Piperazines / pharmacology
  • Receptors, Serotonin / drug effects
  • Serotonin Receptor Agonists / pharmacology

Substances

  • Catecholamines
  • Piperazines
  • Receptors, Serotonin
  • Serotonin Receptor Agonists
  • 1-(3-chlorophenyl)piperazine
  • Epinephrine