Abstract
Three novel bisabolane-type sesquiterpenoids, phyllaemblic acids B (1) and C (2) and phyllaemblicin D (3), together with two new phenolic glycosides, 2-carboxylmethylphenol 1-O-beta-D-glucopyranoside (4) and 2,6-dimethoxy-4-(2-hydroxyethyl)phenol 1-O-beta-D-glucopyranoside (5), were isolated from the roots of Phyllanthus emblica. The structures of 1-5 were established by spectral and chemical methods. The absolute stereochemistry of 1 and 2 was determined by applying the PGME method.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Euphorbiaceae / chemistry*
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Glucosides / chemistry*
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Glucosides / isolation & purification
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Magnetic Resonance Spectroscopy
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Medicine, Chinese Traditional
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Molecular Conformation
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Molecular Structure
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Phytotherapy
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Plant Roots / chemistry
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Plants, Medicinal / chemistry*
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Sesquiterpenes / chemistry
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Sesquiterpenes / isolation & purification*
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Structure-Activity Relationship
Substances
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2,6-dimethoxy-4-(2-hydroxyethyl)phenol 1-O-glucopyranoside
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2-carboxylmethylphenol 1-O-glucopyranoside
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Glucosides
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Sesquiterpenes
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phyllaemblic acid B
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phyllaemblic acid C
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phyllaemblicin D