Objective: To determine the relationship between pregnancy induced hypertension (PIH) and acute disseminated intravascular coagulation (DIC).
Methods: 26 cases with PIH complicated acute DIC were analyzed retrospectively in five hospitals of Xi'an from 1980 to 1997.
Results: (1) In 26 patients with PIH complicated acute DIC, 7 cases died (26.92%), while 17 neonates died (58.62%) in 29 neonates (3 cases were twin pregnancy). Cesarean section and hysterectomy were performed on 7 cases respectively, including 4 cases underwent both of them. (2) The causative factors of PIH complicated acute DIC included placental abruption (7 cases), amniotic fluid embolism (4 cases), eclamptic seizure (4 cases), surgical injury (7 cases) and bleeding (4 cases). 7 cases induced by placental abruption were all cured, 4 cases induced by amniotic fluid embolism all died.
Conclusion: There are close relationship between PIH and DIC, PIH complicated acute DIC is the major cause of maternal and perinatal mortality, special attention should be paid on preventing DIC for PIH.