[A preliminary report on the treatment of pleural carcinomatosis with SMANCS]

M Kimura; H Kaneda; S Kume; H Matsushita; M Inoue; M Kai; H Takeuchi; K Uemura

[A preliminary report on the treatment of pleural carcinomatosis with SMANCS]

Gan To Kagaku Ryoho. 2001 Jul;28(7):1023-5.

[Article in Japanese]

Authors

M Kimura¹, H Kaneda, S Kume, H Matsushita, M Inoue, M Kai, H Takeuchi, K Uemura

Affiliation

¹ Dept. of Surgery, Health Insurance Hitoyoshi General Hospital.

PMID: 11478133

Abstract

To clarify the effect of SMANCS on malignant pleural carcinomatosis, seven patients with malignant pleural effusion were treated with SMANCS administered via an intracavitary route. Five patients showed improvement after one or two injections of SMANCS into the thoracic cavity, although 2 patients needed further therapy with the immunopotentiating agent picibanil (OK-432). No serious adverse effects were observed. This simple therapeutic tactic with SMANCS may be effective in cases of malignant pleural carcinomatosis.

Publication types

English Abstract

MeSH terms

Aged
Antineoplastic Agents / therapeutic use*
Breast Neoplasms / complications
Colonic Neoplasms / complications
Female
Humans
Lung Neoplasms / complications
Male
Maleic Anhydrides / administration & dosage
Maleic Anhydrides / therapeutic use*
Middle Aged
Pleural Effusion, Malignant / drug therapy*
Pleural Effusion, Malignant / etiology
Polystyrenes / administration & dosage
Polystyrenes / therapeutic use*
Stomach Neoplasms / complications
Zinostatin / administration & dosage
Zinostatin / analogs & derivatives
Zinostatin / therapeutic use*

Substances

Antineoplastic Agents
Maleic Anhydrides
Polystyrenes
poly(maleic acid-styrene)neocarzinostatin
Zinostatin