A no-mix orthodontic adhesive composed of primer and paste was developed. The adhesive eliminated the spatulation procedure to which most commercially available products were imperative, could quickly polymerize and cure by means of contact and slight compression of the primer with the paste. It featured high bond strength, convenient handling, enough working time, easy removal of extra adhesive around the bracket and no objectionable odour. The biological tests showed it was safe to use in orthodontic practice, and the results of clinical trials certified the reliable performance, effective bond and convenient use of the adhesive.