Kainic acid induces selective mitochondrial oxidative phosphorylation enzyme dysfunction in cerebellar granule neurons: protective effects of melatonin and GSH ethyl ester

FASEB J. 2001 Aug;15(10):1786-8. doi: 10.1096/fj.00-0427fje.
No abstract available

MeSH terms

  • Animals
  • Antioxidants / pharmacology
  • Cell Survival / drug effects
  • Cerebellum / cytology
  • Electron Transport Complex II
  • Glutathione / analogs & derivatives
  • Glutathione / pharmacology*
  • Kainic Acid / pharmacology*
  • Melatonin / pharmacology*
  • Mitochondria / enzymology*
  • Multienzyme Complexes / metabolism
  • Neurons / ultrastructure*
  • Oxidative Phosphorylation / drug effects*
  • Oxidoreductases / metabolism
  • Rats
  • Reactive Oxygen Species / metabolism
  • Succinate Dehydrogenase / metabolism

Substances

  • Antioxidants
  • Multienzyme Complexes
  • Reactive Oxygen Species
  • S-ethyl glutathione
  • Oxidoreductases
  • Electron Transport Complex II
  • Succinate Dehydrogenase
  • Glutathione
  • Melatonin
  • Kainic Acid