Syngeneic consecutive rat spleen transplantation bearing infantile testis

Microsurgery. 2001;21(4):166-9. doi: 10.1002/micr.1032.

Abstract

Seventy-seven Lewis adult rats received autologous testicular implants in the spleen. These spleens were retransplanted in a consecutive transplant fashion as we described earlier. Some were observed as long as 26 to 27 months. Although earlier splenic-testicular transplants showed benign granulosa cell tumors, some of the long-term follow-ups showed a seminoma-like transformation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Transformation, Neoplastic / pathology*
  • Male
  • Microsurgery*
  • Rats
  • Rats, Inbred Lew
  • Seminoma / pathology*
  • Spleen / pathology
  • Spleen / transplantation*
  • Testicular Neoplasms / pathology*
  • Testis / pathology
  • Testis / transplantation*
  • Transplantation, Isogeneic