Abstract
Nucleotide sequence and phylogenetic analysis of the VP1 structural protein have been used extensively as diagnostic and epidemiological tools for foot and mouth disease virus (FMDV). In this report we have applied this methodology to the analysis of the VP1 coding sequence from FMDV strains isolated in Argentina during 1993-1994. The results demonstrated that the field isolates were related to the vaccine strains used at that time. However the involvement of the vaccine virus appeared to be different for outbreaks caused by FMD viruses type O or C. These data provide a database essential for determining the origin of new epizootics.
Publication types
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Comparative Study
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English Abstract
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antigens, Viral / genetics
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Antigens, Viral / immunology
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Aphthovirus / classification
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Aphthovirus / genetics
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Aphthovirus / immunology
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Aphthovirus / isolation & purification*
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Argentina / epidemiology
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Base Sequence
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Capsid / genetics*
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Capsid Proteins
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Cattle
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Cattle Diseases / epidemiology
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Cattle Diseases / transmission
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Cattle Diseases / virology*
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Disease Outbreaks
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Foot-and-Mouth Disease / epidemiology
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Foot-and-Mouth Disease / transmission
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Foot-and-Mouth Disease / virology*
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Molecular Sequence Data
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Phylogeny
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RNA, Viral / genetics
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Retrospective Studies
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Sequence Alignment
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Sequence Homology, Nucleic Acid
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Serotyping
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Viral Vaccines / adverse effects
Substances
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Antigens, Viral
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Capsid Proteins
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RNA, Viral
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VP1 protein, Foot-and-mouth disease virus
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Viral Vaccines