Discovery of estrogen sulfotransferase inhibitors from a purine library screen

J Med Chem. 2001 Aug 16;44(17):2683-6. doi: 10.1021/jm010171u.

Authors

D E Verdugo¹, M T Cancilla, X Ge, N S Gray, Y T Chang, P G Schultz, M Negishi, J A Leary, C R Bertozzi

Affiliation

¹ Center for New Directions in Organic Synthesis, Howard Hughes Medical Institute, and Department of Chemistry, University of California, Berkeley, California 94720, USA.

PMID: 11495578
DOI: 10.1021/jm010171u

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chromatography, Thin Layer
Combinatorial Chemistry Techniques
Enzyme Inhibitors / chemical synthesis*
Enzyme Inhibitors / chemistry
Enzymes, Immobilized
Mass Spectrometry
Purines / chemical synthesis*
Purines / chemistry
Sepharose
Sulfotransferases / antagonists & inhibitors*

Substances

Enzyme Inhibitors
Enzymes, Immobilized
Purines
Sepharose
Sulfotransferases
estrone sulfotransferase