[Culture of chondrocytes using allogenous acellular cartilaginous matrix]

Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi. 1999 May;15(3):178-9.
[Article in Chinese]

Abstract

Objective: To observe the effect of chondrocyte culture with natural ECM made from allogenous acellular cartilage.

Methods: The allogenous acellular cartilaginous matrix was used as a scaffold in chondrocyte culture in vitro, comparing with the acellular perichondrium. The growth and regeneration of the chondrocytes in vitro were observed.

Results: The chondrocytes seeded on the acellular cartilaginous matrix grew well while the chondrocytes on the acellular perichondrium matrix grew poorly.

Conclusion: The surface condition of the scaffold has a notable influence on the growth of the cells. The allogenous acellular cartilaginous matrix may provide a suitable condition for chondrocytes, and it has the possibility to be developed as a natural scaffold for tissue engineering.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Cells, Cultured
  • Chondrocytes / cytology*
  • Coculture Techniques
  • Ear Cartilage / cytology*
  • Extracellular Matrix*
  • Rabbits
  • Tissue Transplantation / methods