Objective: To study the therapeutic effect of blood activating polypeptide on chronic severe viral hepatitis (CSH) and the method used.
Methods: The treated group included 50 CSH patients (male 82, female 8, age 39 +/- 9). Based on routine treatments, they were intravenously injected with 15 ml blood activating polypeptide dissolved in 250 ml of 10% glucose, qd x 4 wks. The control group contained 50 CSH patients (male 3, female 7, age 38+/-12). They were only treated with routine treatments for liver protection, jaundice regression, health maintenance, anti-infection and diuresis.
Results: The SB and ALT in treated patients decreased obviously (P < 0.01) after treatment, the prominent efficacy was 52%, the total efficacy was 86%, all were superior to the control group.
Conclusions: Blood activating polypeptide is safe, reliable and effective in the treatment of CSH.