Nucleocytoplasmic transport: diffusion channel or phase transition?

Curr Biol. 2001 Jul 24;11(14):R551-4. doi: 10.1016/s0960-9822(01)00340-2.

Abstract

How exactly large molecules translocate through nuclear pores has been mysterious for a long time. Recent kinetic measurements of transport rates through the pore have led to a novel translocation model that elegantly combines selectivity with very high transport rates.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Active Transport, Cell Nucleus / physiology*
  • Animals
  • Biological Transport, Active
  • Cytoplasm / metabolism*
  • Models, Biological
  • Nuclear Pore / metabolism*
  • Nuclear Proteins / chemistry
  • Nuclear Proteins / metabolism
  • Repetitive Sequences, Amino Acid

Substances

  • Nuclear Proteins