Rhinovirus RNA in the maxillary sinus epithelium of adult patients with acute sinusitis

Clin Infect Dis. 2001 Sep 15;33(6):909-11. doi: 10.1086/322678. Epub 2001 Aug 10.

Abstract

We used in situ hybridization for the detection of rhinovirus in maxillary sinus biopsy specimens obtained from 14 adult patients with acute sinusitis. In 7 specimens, rhinovirus RNA could be demonstrated in the maxillary sinus epithelium, thereby confirming the etiology of rhinovirus and the clinical suspicion of acute sinusitis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Adult
  • Epithelium / virology
  • Female
  • Humans
  • In Situ Hybridization
  • Male
  • Maxillary Sinus / virology
  • Maxillary Sinusitis / virology*
  • Picornaviridae Infections / virology
  • RNA, Viral / genetics
  • RNA, Viral / isolation & purification*
  • Rhinovirus / genetics
  • Rhinovirus / isolation & purification*

Substances

  • RNA, Viral