Inhibition of polyol pathway activity in diabetic and galactosemic rats by the aldose reductase inhibitor CP-45,634

Adv Exp Med Biol. 1979:119:347-56. doi: 10.1007/978-1-4615-9110-8_51.
No abstract available

MeSH terms

  • Aldehyde Reductase / antagonists & inhibitors*
  • Animals
  • Blood Glucose / metabolism
  • Cattle
  • Diabetes Mellitus, Experimental / metabolism*
  • Galactitol / metabolism*
  • Galactosemias / metabolism*
  • Lens, Crystalline / enzymology
  • Male
  • Rats
  • Sciatic Nerve / drug effects
  • Sciatic Nerve / metabolism
  • Sorbitol / metabolism*
  • Sugar Alcohol Dehydrogenases / antagonists & inhibitors*
  • Sugar Alcohols / metabolism*

Substances

  • Blood Glucose
  • Sugar Alcohols
  • Galactitol
  • Sorbitol
  • Sugar Alcohol Dehydrogenases
  • Aldehyde Reductase