Corticosteroid therapy reversed progressive chronic granulomatous lung disease following deterioration on interferon-gamma treatment

A Halamish; A Klar; D Shoseyov; G Blinder; H Hurvitz

doi:10.1002/ppul.1116

Corticosteroid therapy reversed progressive chronic granulomatous lung disease following deterioration on interferon-gamma treatment

Pediatr Pulmonol. 2001 Sep;32(3):257-60. doi: 10.1002/ppul.1116.

Authors

A Halamish¹, A Klar, D Shoseyov, G Blinder, H Hurvitz

Affiliation

¹ Department of Pediatrics, Bikur Cholim General Hospital, Hebrew University-Hadassah Medical School, Jerusalem, Israel.

PMID: 11536456
DOI: 10.1002/ppul.1116

Abstract

We describe a patient who suffered from chronic progressive granulomatous lung disease. He had no clinical or microbiological evidence of infection. After failure of treatment with interferon-gamma and trimethoprim-sulfamethoxazole, he responded dramatically to corticosteroids.

Publication types

Case Reports

MeSH terms

Adrenal Cortex Hormones / pharmacology
Adrenal Cortex Hormones / therapeutic use*
Anti-Infective Agents / pharmacology
Antiviral Agents / pharmacology*
Child
Disease Progression
Drug Resistance
Granulomatous Disease, Chronic / drug therapy*
Granulomatous Disease, Chronic / immunology
Humans
Interferon-gamma / pharmacology*
Lung Diseases / congenital*
Lung Diseases / drug therapy*
Lung Diseases / pathology
Male
Treatment Outcome
Trimethoprim, Sulfamethoxazole Drug Combination / pharmacology

Substances

Adrenal Cortex Hormones
Anti-Infective Agents
Antiviral Agents
Trimethoprim, Sulfamethoxazole Drug Combination
Interferon-gamma