[3H-Diazepam binding in the brain of intact animals with various reactivity to emotional stress]

S B Seredenin; M A Iarkova; M V Voronin

[3H-Diazepam binding in the brain of intact animals with various reactivity to emotional stress]

Eksp Klin Farmakol. 2001 Jan-Feb;64(1):63-5.

[Article in Russian]

Authors

S B Seredenin¹, M A Iarkova, M V Voronin

Affiliation

¹ Laboratory of Pharmacogenetics, Institute of Pharmacology, Russian Academy of Medical Sciences, Baltiiskaya ul. 8, Moscow, 125315 Russia.

PMID: 11544809

Abstract

Open-field tests revealed a significant decrease in the degree of H3-diazepam binding in the brain of BALB/c mice and MR rats. No such effects were observed in the C57BL/6 and MNRA strains. No interstrain distinctions were observed in the intact animals.

Publication types

English Abstract

MeSH terms

Animals
Brain / metabolism*
Diazepam / metabolism*
Male
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Radioligand Assay
Rats
Rats, Inbred Strains
Receptors, GABA-A / metabolism*
Species Specificity
Stress, Psychological / metabolism*

Substances

Receptors, GABA-A
Diazepam