Sweeping of membranes vs. intracervical prostaglandin E2 gel for cervical ripening. Randomized trial

J Reprod Med. 2001 Aug;46(8):706-8.

Abstract

Objective: To compare intracervical prostaglandin E2 gel and membrane sweeping for cervical ripening.

Study design: Fifty patients were randomized to either intracervical prostaglandin E2 or membrane sweeping. A Bishop score was assigned by a blinded examiner prior to and 24 hours following the procedure.

Results: The Bishop scores assigned 24 hours after prostaglandin instillation and membrane sweeping were not significantly different (3.4, SE 0.42, vs. 3.3, SE 0.37, respectively; P > .05). The proportions of women entering active labor or delivering within 24 hours were similar in the prostaglandin and membrane groups (21% and 19%, respectively; P > .05).

Conclusion: When both intracervical prostaglandin insertion and membrane sweeping are feasible, their salutary effects are comparable.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Administration, Intravaginal
  • Adult
  • Cervical Ripening / drug effects*
  • Dinoprostone / administration & dosage
  • Dinoprostone / therapeutic use*
  • Female
  • Humans
  • Labor, Induced / methods*
  • Pregnancy

Substances

  • Dinoprostone