Regulation of protein synthesis by insulin through IRS-1

Prog Mol Subcell Biol. 2001:26:49-93. doi: 10.1007/978-3-642-56688-2_3.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Calcium-Calmodulin-Dependent Protein Kinases / antagonists & inhibitors
  • Cell Division
  • Cell Line
  • Enzyme Activation
  • Eukaryotic Initiation Factor-2B / metabolism
  • Glycogen Synthase Kinase 3
  • Humans
  • Insulin / metabolism*
  • Insulin Receptor Substrate Proteins
  • Intracellular Signaling Peptides and Proteins
  • Mice
  • Mitogen-Activated Protein Kinases / metabolism
  • Models, Biological
  • Phosphatidylinositol 3-Kinases / metabolism
  • Phosphoproteins / metabolism*
  • Protein Biosynthesis*
  • Protein Kinases / metabolism
  • Protein Tyrosine Phosphatase, Non-Receptor Type 11
  • Protein Tyrosine Phosphatase, Non-Receptor Type 6
  • Protein Tyrosine Phosphatases / metabolism
  • Rats
  • Receptor, Insulin / metabolism
  • Signal Transduction / drug effects
  • Sirolimus / pharmacology
  • TOR Serine-Threonine Kinases

Substances

  • Eukaryotic Initiation Factor-2B
  • IRS1 protein, human
  • Insulin
  • Insulin Receptor Substrate Proteins
  • Intracellular Signaling Peptides and Proteins
  • Irs1 protein, mouse
  • Irs1 protein, rat
  • Phosphoproteins
  • Protein Kinases
  • MTOR protein, human
  • mTOR protein, mouse
  • mTOR protein, rat
  • Receptor, Insulin
  • TOR Serine-Threonine Kinases
  • Calcium-Calmodulin-Dependent Protein Kinases
  • Mitogen-Activated Protein Kinases
  • Glycogen Synthase Kinase 3
  • PTPN11 protein, human
  • PTPN6 protein, human
  • Protein Tyrosine Phosphatase, Non-Receptor Type 11
  • Protein Tyrosine Phosphatase, Non-Receptor Type 6
  • Protein Tyrosine Phosphatases
  • Ptpn11 protein, mouse
  • Ptpn11 protein, rat
  • Ptpn6 protein, mouse
  • Ptpn6 protein, rat
  • Sirolimus