GABAergic and NPY-Y(1) network in the medial amygdala: a neuroanatomical basis for their functional interaction

Neuropharmacology. 2001 Oct;41(5):639-42. doi: 10.1016/s0028-3908(01)00109-5.

Abstract

We used Y(1)R/LacZ transgenic mice to investigate the interaction between NPY, GABA and Y(1) receptors in the amygdala. Immunolabeling of GABA and NPY positive neurons and histochemical staining of beta-galactosidase revealed NPY and GABA colocalization and close contacts of NPY-positive fibers with GABAergic neurons also expressing the Y(1)R/LacZ transgene.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amygdala / anatomy & histology*
  • Amygdala / metabolism*
  • Animals
  • Gene Expression / physiology
  • Male
  • Mice
  • Mice, Transgenic
  • Nerve Net / metabolism
  • Neuropeptide Y / metabolism
  • Neuropeptide Y / physiology*
  • Receptors, GABA / metabolism
  • Receptors, GABA / physiology*
  • Receptors, Neuropeptide Y / metabolism
  • Receptors, Neuropeptide Y / physiology*

Substances

  • Neuropeptide Y
  • Receptors, GABA
  • Receptors, Neuropeptide Y
  • neuropeptide Y-Y1 receptor