Equine rhinitis B virus: a new serotype

J Gen Virol. 2001 Nov;82(Pt 11):2641-2645. doi: 10.1099/0022-1317-82-11-2641.

Abstract

Equine rhinovirus serotype 3 isolate P313/75 was assigned, with an unclassified genus status, to the family PICORNAVIRIDAE: The sequence from the 5' poly(C) tract to the 3' poly(A) tract of P313/75 was determined. The sequence is 8821 bases in length and contains a potential open reading frame for a polyprotein of 2583 amino acids. Sequence comparison and phylogenic analysis suggest that P313/75 is most closely related to the prototype equine rhinitis B virus (ERBV) strain P1436/71, formerly named equine rhinovirus type 2. A high degree of sequence similarity was found in the P2 and P3 regions of the two genomes. However, the deduced amino acid sequences of the P1 region of P313/75 and ERBV strain P1436/71 contained significant differences, which presumably account for the serological segregation of the two viruses. It is suggested that P313/75 can be classified as a new serotype of the genus Erbovirus, tentatively named ERBV2. Seroepidemiological data indicate that ERBV2 infection of horses may be common (24%) in Australia.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Antibodies, Viral / blood
  • Aphthovirus / chemistry
  • Aphthovirus / classification*
  • Aphthovirus / genetics
  • Australia / epidemiology
  • Horse Diseases / epidemiology
  • Horse Diseases / virology*
  • Horses
  • Molecular Sequence Data
  • Picornaviridae Infections / epidemiology
  • Picornaviridae Infections / veterinary*
  • Picornaviridae Infections / virology
  • Poly A
  • Poly C
  • Sequence Analysis, DNA
  • Serotyping

Substances

  • Antibodies, Viral
  • Poly A
  • Poly C

Associated data

  • GENBANK/AF361253