Intravenous regional anaesthesia using lignocaine and tramadol

Ann Acad Med Singap. 2001 Sep;30(5):516-9.

Abstract

Introduction: This prospective, randomised, double-blind study was designed to assess if the addition of 50 mg tramadol to 30 mL 0.5% lignocaine would improve the efficacy of intravenous regional anaesthesia.

Materials and methods: Fifty-four adult patients undergoing upper limb surgery were randomly allocated to receive either 30 mL 0.5% lignocaine and 1 mL normal saline (group A) or 30 mL 0.5% lignocaine and 50 mg tramadol (group B). They were then assessed for onset of sensory and motor block and the VbAS score for tourniquet pain.

Results: Although more patients in group B had a faster onset of sensory and motor block, this was not significantly different. Patients in group B had a significantly lower VbAS score 30 min after tourniquet inflation and after change over to the distal tourniquet (P < 0.05). There were no complaints of postoperative nausea and vomiting. Two patients in group B developed localised skin urticaria of the forearm which resolved with the release of the tourniquet.

Conclusion: There is a positive trend that tramadol might improve the quality of intravenous regional anaesthesia.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Analgesics, Opioid / administration & dosage*
  • Anesthesia, Intravenous / methods*
  • Anesthetics, Combined / administration & dosage*
  • Anesthetics, Local / administration & dosage*
  • Arm / surgery
  • Double-Blind Method
  • Female
  • Humans
  • Lidocaine / administration & dosage*
  • Male
  • Middle Aged
  • Nerve Block
  • Pain Measurement
  • Prospective Studies
  • Singapore
  • Tourniquets
  • Tramadol / administration & dosage*

Substances

  • Analgesics, Opioid
  • Anesthetics, Combined
  • Anesthetics, Local
  • Tramadol
  • Lidocaine