Steady state of an inhibitory neural network

Phys Rev E Stat Nonlin Soft Matter Phys. 2001 Oct;64(4 Pt 1):041906. doi: 10.1103/PhysRevE.64.041906. Epub 2001 Sep 20.

Abstract

We investigate the dynamics of a neural network where each neuron evolves according to the combined effects of deterministic integrate-and-fire dynamics and purely inhibitory coupling with K randomly chosen "neighbors." The inhibition reduces the voltage of a given neuron by an amount Delta when one of its neighbors fires. The interplay between the integration and inhibition leads to a steady state that is determined by solving the rate equations for the neuronal voltage distribution. We also study the evolution of a single neuron and find that the mean lifetime between firing events equals 1+K delta and that the probability that a neuron has not yet fired decays exponentially with time.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Algorithms
  • Biophysical Phenomena
  • Biophysics
  • Humans
  • Models, Anatomic
  • Nerve Net*
  • Neurons / pathology*
  • Thermodynamics